Also, Andrew Luck and the Indianapolis Colts travel to take on their old coach Bruce Arias - and last year's Coach of the Year award winner, and the Arizona Cardinals, while Tony Romo and the Dallas Cowboys head to the Big Apple to take on the New York Giants, looking to become the first team to win five games in a row after losing their first six games of the season.
Also, the Green Bay Packers play without injured QB Aaron Rodgers as they host the Philadelphia Eagles, the Chicago Bears and Detroit Lions square off in a crucial NFC North division game, while Cam Newton and the surging Carolina Panthers travel to San Francisco to face Colin Kaepernick and the 49ers.
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The superhero movie "Deadpool" has crushed box-office records despite the restricted rating (Rated R) given to the film.
This was the first time in their 52 years in the industry to reveal three cover girls.